Novel multitarget tacrine derivatives: design and structure activity relationship

Authors :: Krunić, Mihajlo
Jevtić, Ivana
Penjišević, Jelena
Kostić-Rajačić, Slađana
Source :: Book of abstracts-EFMC-YMCS-Young Medicinal Chemists' Symposium, September 8-9, 2022, Nice, France
Publication Year :: 2022
Publisher :: European Federation for Medicinal chemistry and Chemical biology (EFMC), 2022.
Abstract: Alzheimer's disease (AD) is a serious, neurodegenerative disease, characterized with a progressive loss of cognitive and behavioral functions leading to fatal outcome. Tacrine belongs to a class of cholinesterase inhibitors(ChEls) and it is the first ChEI marketed for the treatment of AD symptoms.

Language :: English
Database :: OpenAIRE
Journal :: Book of abstracts-EFMC-YMCS-Young Medicinal Chemists' Symposium, September 8-9, 2022, Nice, France
Accession number :: edsair.od......4273..a9b0047c2f23cc04e71c8bee6c339ed5

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