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Radio-protective effect of DMSO glycerol in human non-small cell lung cancer irradiated with gamma rays

Authors :
Petković, Vladana
Keta, Otilija D.
Vojinović, N.
Incerti, Sebastien
Petrović, Ivan M.
Ristić-Fira, Aleksandra
Source :
Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry
Publication Year :
2016
Publisher :
Society of Physical Chemists of Serbia, 2016.

Abstract

Direct effects of radiation affect the DNA molecule, causing DNAdamage and finally cell death. We examined the role of DMSO and glycerol as free-radical scavengers in HTB177 cells irradiated with gamma rays. Direct effects of radiation were estimated through DNA double strand break (DSB) quantification and cell survival. Results of this work revealed that chosen concentration of DMSO exhibit higher protective effect comparing to glycerol. Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 26-30 September 2016.

Details

Language :
English
Database :
OpenAIRE
Journal :
Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry
Accession number :
edsair.od......4175..783585c0966a0e4d36f2ac2c3b2b8711