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Minimum information about a protein affinity reagent (MIAPAR)

Authors :
Bourbeillon, Julie
Orchard, Sandra
Benhar, Itai
Borrebaeck, Carl A.k.
De Daruvar, Antoine
Dubel, Stefan
Frank, Ronald
Gibson, Frank
Gloriam, David
Haslam, Niall
Hiltker, Tara
Humphrey-Smith, Ian
Hust, Michael
Juncker, David
Koegll, Manfred
Konthur, Zoltan
Korn, Bernhard
Krobitsch, Sylvia
Muyldermans, Serge
Nygren, Per-Ake
Palcy, Sandrine
Polic, Bojan
Rodriguez, Henry
Sawyer, Alan
Schlapshy, Martin
Snyder, Michael
Stoevesandt, Oda
Taussig, Michael J.
Templin, Markus
Uhlen, Mathias
Van Der Maarel, Silvere
Cellular and Molecular Immunology
Publication Year :
2010
Publisher :
Nature Publishing Group, 2010.

Abstract

We wish to alert your readers to MIAPAR, the minimum information about a protein affinity reagent. This is a proposal developed within the community as an important first step in formalizing standards in reporting the production and properties of protein binding reagents, such as antibodies, developed and sold for the identification and detection of specific proteins present in biological samples. It defines a checklist of required information, intended for use by producers of affinity reagents, quality-control laboratories, users and databases (Supplementary Table 1). We envision that both commercial and freely available affinity reagents, as well as published studies using these reagents, could include a MIAPAR-compliant document describing the product's properties with every available binding partner. This would enable the user or reader to make a fully informed evaluation of the validity of conclusions drawn using this reagent

Subjects

Subjects :
Standards
protein affinity reagent

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.od......3848..30a5deb9ee8ba0a7aa202c2555cf5e1d