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Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

Authors :
Dudakovic, A.
Camilleri, E. T.
Lewallen, E. A.
McGee-Lawrence, M. E.
Riester, S. M.
Kakar, S.
Montecino, M.
Stein, G. S.
Ryoo, H-M.
Dietz, H.
Westendorf, J. J.
van Wijnen, A. J.
Source :
Journal of Cellular Physiology, Artículos CONICYT, CONICYT Chile, instacron:CONICYT
Publication Year :
2014

Abstract

Human adipose-derived mesenchymal stromal cells (AMSCs) grown in platelet lysate are promising agents for therapeutic tissue regeneration. Here, we investigated whether manipulation of epigenetic events by the clinically relevant histone deacetylase inhib

Details

Language :
English
Database :
OpenAIRE
Journal :
Journal of Cellular Physiology, Artículos CONICYT, CONICYT Chile, instacron:CONICYT
Accession number :
edsair.od......3056..bbcbd89c4e95fe655e87ccc98e84d11d