Granulomatous lymphadenitis in swine: validation of national data based on identification by the service of federal inspection (SFI)

The granulomatous lymphadenitis (GL) in pigs is mainly caused by Mycobacterium avium hominissuis (MAH), who belongs to the Mycobacterium avium Complex (MAC), considered non-tuberculous mycobacteria (NTM). Although GL does not affect swine zootecnical performance, economic losses occur during the slaughter line by condemning viscera and carcasses. The lesion is characterized by one or more foci of granuloma, which most frequently affect the organs of the digestive tract and peripheral lymph nodes. The main differential diagnosis encompasses Mycobacterium bovis (M. bovis) and Mycobacterium tuberculosis (M. tuberculosis), who belongs to the Mycobacterium tuberculosis Complex (MTbC), of relevant zoonotic potential. Nevertheless macroscopic examinations and histopathology are insufficient to determine the etiologic agent involved. Federal Meat Inspection had registered the frequency of 0,81 % of lymphadenitis in Brazil from 2012 to 2014. The aim of this study was to investigate the etiology of the granulomatous lesions for validation of the national data of inspection and build a database to further risk analysis. Made available in DSpace on 2020-09-17T04:41:05Z (GMT). No. of bitstreams: 1 final9436.pdf: 671691 bytes, checksum: 67aa8f9948f0d9730438802e8c73b6f6 (MD5) Previous issue date: 2019