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Non-invasive assessment of ?-carotene levels in the skin of colombian adults
- Source :
- Repositorio EdocUR-U. Rosario, Universidad del Rosario, instacron:Universidad del Rosario
- Publication Year :
- 2012
-
Abstract
- Introduction: Carotenoid pigments have antioxidant properties beneficial for human health. Use of resonance Raman spectroscopy (RRS) as a reliable method for measuring carotenoid levels in tissues such as dermis has been suggested. However, data about the variability and reproducibility of this technique should be collected before it can be used. Objective: To assess reproducibility of RRS for detection of total ?-carotene levels in the skin of Colombian adults. Design: Forty-eight healthy men and 30 healthy women with various pigmentation levels were enrolled into the study. Measurements by RRS were performed in the palmar region and medial and lateral aspects of the arms. Odds ratio and 95% confidence intervals were calculated, adjusting for confounding factors: body mass index, waist circumference, percent body fat, age, race, smoking, and sex. Reproducibility of the technique was estimated using intraclass correlation coefficient (ICC). Results: Mean ?-carotene levels were 29.9±11.9 in men and 30.6±8.6 in women (. P=.787). No differences or significant associations were found of ?-carotene levels with confounding factors assessed by sex. ICCs were 0.89 in the palmar region, 0.85 in the medial aspect of arm, and 0.82 in the external aspect of arm. Conclusion: RRS spectroscopy is a reliable method for non-invasive measurement of ?-carotene levels in skin, and may be used as an important biomarker of antioxidant status in nutritional and health studies in humans. © 2012 SEEN.
- Subjects :
- Male
Adult
Reproducibility of results
raman
Race
Adolescent
Major clinical study
Colombia
Ethnic groups
Article
Non invasive measurement
Nutritional status
Confounding factors (epidemiology)
Humans
Adults
Raman spectrometry
Middle aged
Skin pigmentation
Spectroscopy
Nutrition
Skin
Aged
Beta carotene
Biological markers
Anthropometry
Smoking
?-carotenes
Reproducibility
Spectrum analysis
Oxidation-reduction
Correlation coefficient
Young adult
Body mass
Body fat
Arm
Cross-sectional studies
Waist circumference
Female
Sex factors
Age factors
Human
Subjects
Details
- Language :
- Spanish; Castilian
- Database :
- OpenAIRE
- Journal :
- Repositorio EdocUR-U. Rosario, Universidad del Rosario, instacron:Universidad del Rosario
- Accession number :
- edsair.od......3056..4161089f3e52f73d69ed7591c3e24f95