Selected QEEG variables in early prediction of response to antidepressant treatment

Electroencephalography is a sensitive method that is able to register neurophysiological changes (operations) in the cerebral cortex, which can be interpreted on the basis of the outputs of various complex computational transformations and in accordance with current neuroscience knowledge. The dynamic course of electrocortical activity is conditioned by functional and structural processes, which can have their origin both in the cortex itself and in various subcortical areas that are associated with it. The development of mathematical methods for the analysis of biological signals (respectively the development of the theory and practice of signal processing in general) has enabled a significant increase in EEG information yield, which is now far from limited to visual inspection of EEG recordings (although it still remains very important for the clinic). Current computer-controlled analysis of EEG signals from individual electrodes allows to obtain a valid reflection of neuronal activity derived from the values of various variables of quantitative electroencephalography (QEEG; spectral power, asymmetry, cordance, frequency peak, current density distribution, etc.), which can specifically correlate with psychopathological processes. Important QEEG methods in electrophysiology include those that are...