Complexes of macrocyclic ligands

Macrocyclic ligands are compounds well-known and studied for their ability to bind metal ions into complexes possessing high kinetic inertness and thermodynamic stability. These properties make such compounds useful in medicine. This thesis focuses on ligand cis- DO2A2P, which belongs to a series of ligands based on cyclen skeleton with mixed acetate and phosphonate pendant arms. A lot of attention has been paid to the other members of this ligands series, but the information about cis-DO2A2P is still incomplete. In this thesis, the complexation properties of mentioned ligand were studied, as well as properties of its complexes with the lanthanide ions in solution. Key words Macrocycles; polydentate ligands; lanthanides; transition metals; organophosphorus acids