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Intratumoral CD8+ T cells with stem cell-like properties: Implications for cancer immunotherapy

Authors :
Held, W.
Siddiqui, I.
Schaeuble, K.
Speiser, D.E.
Source :
Science translational medicine, vol. 11, no. 515, pp. eaay6863
Publication Year :
2019

Abstract

Intratumoral PD-1 + TCF1 + CD8 + T cells with stem cell-like properties mediate cellular expansion and tumor control in response to immunotherapy.

Details

Language :
English
Database :
OpenAIRE
Journal :
Science translational medicine, vol. 11, no. 515, pp. eaay6863
Accession number :
edsair.od......1900..fdf61a1a72595d0e52478d78ec55abbc