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Using 3D realistic blood vessel structures machine learning for MR vascular Fingerprinting

Authors :
Delphin, Aurélien
Boux, Fabien
Brossard, Clément
Warnking, Jan
Lemasson, Benjamin
Barbier, Emmanuel
Christen, Thomas
Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, 38000, Grenoble, France
Laboratoire Rhéologie et Procédés (LRP)
Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )
Université Grenoble Alpes (UGA)
MoGlimaging Network, HTE Program of the French Cancer Plan, Toulouse, France
Delphin, Aurélien
Source :
ISMRM 31st Annual Meeting & Exhibition, May 2022, London, United Kingdom, ISMRM 31st Annual Meeting & Exhibition, May 2022, London, United Kingdom, May 2022, London, United Kingdom
Publication Year :
2022
Publisher :
HAL CCSD, 2022.

Abstract

International audience; MR vascular ngerprinting aims at mapping cerebral vascular properties such as blood volume and oxygenation. We to improve the technique by generating dictionaries based 3D vascular networks segmented from whole brain high-resolution (3 µm isotropic) microscopy In order to compensate for the limited number of available data and long times, we used a machine-learning reconstruction process generalize our results and tested our approach in healthy, stroke and tumor animal models. results show high quality maps with expected contrast and baseline values in healthy animals as well expected trends in pathological tissues.

Details

Language :
English
Database :
OpenAIRE
Journal :
ISMRM 31st Annual Meeting & Exhibition, May 2022, London, United Kingdom, ISMRM 31st Annual Meeting & Exhibition, May 2022, London, United Kingdom, May 2022, London, United Kingdom
Accession number :
edsair.od......1398..837fcdc7e860883251d44cc46f4d2986