Col17a1 is a syncytial trophoblast extracellular specific marker significantly elevated in preeclampsia

Human pregnancy is a sterile inflammatory state to which placenta derived soluble factors and syncytial trophoblast extracellular vesicles (STBEVs) contribute. STBEVs numbers have been shown to increase in early-onset preeclampsia (EoPE) but their molecular signatures are incompletely characterised.