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Genome-wide association study identifies 48 common genetic variants associated with handedness

Authors :
Cuellar-Partida, Gabriel
Tung, Joyce Y
Eriksson, Nicholas
Albrecht, Eva
Aliev, Fazil
Andreassen, Ole A
Barroso, Inês
Beckmann, Jacques S
Boks, Marco P
Boomsma, Dorret I
Boyd, Heather A
Breteler, Monique MB
Campbell, Harry
Chasman, Daniel I
Cherkas, Lynn F
Davies, Gail
de Geus, Eco JC
Deary, Ian J
Deloukas, Panos
Dick, Danielle M
Duffy, David L
Eriksson, Johan G
Esko, Tõnu
Feenstra, Bjarke
Geller, Frank
Gieger, Christian
Giegling, Ina
Gordon, Scott D
Han, Jiali
Hansen, Thomas F
Hartmann, Annette M
Hayward, Caroline
Heikkilä, Kauko
Hicks, Andrew A
Hirschhorn, Joel N
Hottenga, Jouke-Jan
Huffman, Jennifer E
Hwang, Liang-Dar
Ikram, M Arfan
Kaprio, Jaakko
Kemp, John P
Khaw, Kay-Tee
Klopp, Norman
Konte, Bettina
Kutalik, Zoltan
Lahti, Jari
Li, Xin
Loos, Ruth JF
Luciano, Michelle
Magnusson, Sigurdur H
Mangino, Massimo
Marques-Vidal, Pedro
Martin, Nicholas G
McArdle, Wendy L
McCarthy, Mark I
Medina-Gomez, Carolina
Melbye, Mads
Melville, Scott A
Metspalu, Andres
Milani, Lili
Mooser, Vincent
Nelis, Mari
Nyholt, Dale R
O'Connell, Kevin S
Ophoff, Roel A
Palmer, Cameron
Palotie, Aarno
Palviainen, Teemu
Pare, Guillaume
Paternoster, Lavinia
Peltonen, Leena
Penninx, Brenda WJH
Polasek, Ozren
Pramstaller, Peter P
Prokopenko, Inga
Raikkonen, Katri
Ripatti, Samuli
Rivadeneira, Fernando
Rudan, Igor
Rujescu, Dan
Smit, Johannes H
Smith, George Davey
Smoller, Jordan W
Soranzo, Nicole
Spector, Tim D
Pourcain, Beate St
Starr, John M
Stefánsson, Hreinn
Steinberg, Stacy
Teder-Laving, Maris
Thorleifsson, Gudmar
Stefánsson, Kári
Timpson, Nicholas J
Uitterlinden, André G
van Duijn, Cornelia M
van Rooij, Frank JA
Vink, Jaqueline M
Vollenweider, Peter
Vuoksimaa, Eero
Source :
Nature human behaviour, vol 5, iss 1
Publication Year :
2021
Publisher :
eScholarship, University of California, 2021.

Abstract

Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International Handedness Consortium, we conducted a genome-wide association meta-analysis of handedness (N = 1,766,671). We found 41 loci associated (P

Details

Database :
OpenAIRE
Journal :
Nature human behaviour, vol 5, iss 1
Accession number :
edsair.od.......325..6be7b0d06e3986152ff24339faaff2fd