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1,4‐Dithiane‐2,5‐diol: An Attractive Platform for the Synthesis of Sulfur Containing Functionalized Heterocycles
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- This microreview highlights the utility of 1,4? dithiane?2,5?diol 1 as a source for the in situ generation of 2?mercaptoacetaldehyde 2, a versatile two?carbon synthon featuring both electrophilic and nucleophilic reaction centers widely utilized as an attractive platform for the preparation of sulfur?containing molecules. We discussed the involved chemistry, mainly focusing on its applications to the construction of sulfur?containing heterocyclic compounds including the thiophene and 1,3?thiazole families and other different sulfur?nitrogen and sulfur?oxygen heterocycles which continue to be a pillar of organic synthesis as a result of their broad application in organic and medicinal chemistry.
- Subjects :
- F151 Pharmaceutical Chemistry
F150 Medicinal Chemistry
F160 Organic Chemistry
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.od.........5..1d8e52aa393315b4fdb7abb075657967