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Bail-out extracorporeal membrane oxygenation for hydroxychloroquine intoxication: a warning for COVID-19 health-care givers: a warning for COVID-19 health-care givers

Authors :
Holvoet, Wouter
van Soest, Kaja
Havenith, Thomas
Lorusso, Roberto
van Mook, Walther N. K. A.
Delnoij, Thijs
MUMC+: DA KFT Medische Staf (9)
CTC
MUMC+: MA Med Staf Spec CTC (9)
RS: Carim - V04 Surgical intervention
Intensive Care
MUMC+: MA Medische Staf IC (9)
RS: SHE - R1 - Research (OvO)
MUMC+: MA Med Staf Spec Cardiologie (9)
Source :
Acta Cardiologica, 76(2), 200-203. Routledge/Taylor & Francis Group
Publication Year :
2021

Abstract

This case report describes an intentional intoxication with 18 g of hydroxychloroquine (HCQ) presenting with unconsciousness, ventricular dysrhythmias, cardiogenic shock and pulmonary oedema. Initial treatment consisted of sodium bicarbonate, lipid emulsion, diazepam and norepinephrine. Because of persistent cardiogenic shock veno-arterial extracorporeal membrane oxygenation (V-A ECMO) was successfully used as a bridge to recovery. This case underscores the possible side effects of HCQ and the importance of considering ECMO in cardiogenic shock caused by HCQ intoxication which may occur also in patients with coronavirus disease 2019 (COVID-19) based on the currently frequent use of such a compound.

Details

Language :
English
ISSN :
00015385
Database :
OpenAIRE
Journal :
Acta Cardiologica, 76(2), 200-203. Routledge/Taylor & Francis Group
Accession number :
edsair.narcis........cac97618798abf43260ce2329cf247fa