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De trombosedienst als bron van informatie voor onderzoek bij patiƫnten met hartklepprothesen
- Source :
- Nederlands tijdschrift voor geneeskunde, 136(11), 526-530. Bohn Stafleu van Loghum
- Publication Year :
- 1992
-
Abstract
- A new study design was evaluated for the estimation of the incidence of thromboembolic complications, bleeding complications and endocarditis in patients with prosthetic heart valves. Thromboembolism is a serious complication in patients with artificial heart valves. Consequently lifelong anticoagulation therapy is indicated for such patients. In the Netherlands the intensity of the anticoagulation is monitored by a network of regional anticoagulation services. The computerized patient information system of the Leiden anticoagulation service was used for a two year follow-up study of patients with mechanical heart valves. In these years anticoagulation was monitored in 273 patients with a total follow-up period of 442 patient-years. The incidence figures for thromboembolism, bleeding complications and endocarditis were 0.9/100 patient-years, 5.6/100 patient-years and 0.2/100 patient-years, respectively. The findings are similar to those of classical follow-up studies. This method is not suitable for detection of the direct early postoperative mortality or for follow-up of patient with heterografts. We conclude that the detection and follow-up by means of regional anticoagulation service offers an opportunity to investigate patients with mechanical heart valves in an efficient way without notable selection
Details
- Language :
- Dutch; Flemish
- ISSN :
- 00282162
- Database :
- OpenAIRE
- Journal :
- Nederlands tijdschrift voor geneeskunde, 136(11), 526-530. Bohn Stafleu van Loghum
- Accession number :
- edsair.narcis........8b2f971000c2c38c2e2a43173b87091c