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Artificial nanopores and uses and methods relating thereto
- Publication Year :
- 2021
-
Abstract
- The invention relates to the field of nanopores and the use thereof in analyzing biopolymers, including polypeptides and polynucleotides. Provided is an artificial nanopore comprising a multimeric assembly of subunits, each subunit comprising (i) the transmembrane (TM) sequence of a β-barrel or α-helical pore forming protein fused to the amino acid sequence of (ii) a subunit of a ring-forming protein capable of controlling the transport of a polypeptide or polynucleotide across the TM region of the assembly.
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.narcis........50a9ab85a91149b1e6a44326f6c8bd69