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Multivalent ligands to inhibit the adhesion of Pseudomonas aeruginosa targeting lectin LecA and LecB

Authors :
Yu, Guangyun
Afd Chemical Biology and Drug Discovery
Chemical Biology and Drug Discovery
Pieters, Roland
University Utrecht
Publication Year :
2019
Publisher :
Universiteit Utrecht, 2019.

Abstract

Summary The work described in this thesis focuses on the development of inhibitors for Pseudomonas aeruginosa targeting lectins LecA and LecB to inhibit the adhesion of this pathogen and also its biofilm formation. The specificity of the adhesion process could be also used as a detection handle.

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.narcis........120c86f9c8af2483e53edf76cf816252