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Investigating the “Fetal Side” in Recurrent Pregnancy Loss: Reliability of Cell-Free DNA Testing in Detecting Chromosomal Abnormalities of Miscarriage Tissue

Authors :
Zollino, Silvia D’Ippolito
Giuliana Longo
Daniela Orteschi
Andrea Busnelli
Nicoletta Di Simone
Eleonora Pulcinelli
Giorgia Schettini
Giovanni Scambia
Marcella
Source :
Journal of Clinical Medicine; Volume 12; Issue 12; Pages: 3898
Publication Year :
2023
Publisher :
Multidisciplinary Digital Publishing Institute, 2023.

Abstract

(1) Background: The aim of our study is to evaluate whether cell-free DNA testing can overlap the genetic testing of miscarriage tissue in women with early pregnancy loss (EPL) and length of recurrent pregnancy loss (RPL); (2) Methods: We conducted a prospective cohort study at the Pregnancy Loss Unit of the Fondazione Policlinico Universitario A. Gemelli (IRCCS), Rome, Italy between May 2021 and March 2022. We included women with EPL and length of RPL. Gestational age was >9 weeks + 2 days and 25 and

Details

Language :
English
ISSN :
20770383
Database :
OpenAIRE
Journal :
Journal of Clinical Medicine; Volume 12; Issue 12; Pages: 3898
Accession number :
edsair.multidiscipl..91f0df513cd87332bc35cd598bf600a1
Full Text :
https://doi.org/10.3390/jcm12123898