Finite Time Span of High-intensity Signal on T1-weighted Magnetic Resonance Imaging Produced by a Human Blood Clot Using a Circulating Vessel Phantom System

Background : Following the introduction of non-contrast T1-weighted imaging (T1WI) in magnetic resonance imaging, using the inversion-recovery gradient-echo sequence, many researchers have shown that high-intensity signals (HISs) in carotid and coronary arterial walls indicate the presence of intraplaque hemorrhage or intracoronary thrombus containing methemoglobin. However, the time span of HISs generated by thrombus remains unknown. The aim of this study was to image a circulating vessel phantom with T1WI to determine if flow disturbance causes artifacts, such as a HIS and to perform serial observations of a human blood clot....