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Effect of Praziquantel on Hatching of Schistosoma haematobium Eggs

Authors :
Katsumata, Tatsuya
Migwi, D. K.
Muhoho, N. D.
Kimura, Eisaku
Shimada, Masaaki
Aoki, Yoshiki
Source :
熱帯医学 Tropical medicine. 35(1):17-21
Publication Year :
1993
Publisher :
長崎大学熱帯医学研究所, 1993.

Abstract

The hatchability of Schistosoma haematobium eggs excreted by patients treated with praziquantel (PZQ) was examined. The rate of hatching of the eggs excreted by the patients before treatment was 90.1%. The rates of hatching of the eggs excreted by the patients 3 hr, 24 hr and 48 hr after treatment were 25.5%, 19.2% and 29.9% respectively. In vivo PZQ inhibits the hatching of S. haematobium eggs. The result of in vivo experiment was strongly supported by the results of the in vitro experiments. The hatching of the eggs exposed to PZQ at a concentration of 0.1μg/ml for one hour in vitro was inhibited.<br />熱帯医学 Tropical medicine 35(1). p17-21, 1993

Details

Language :
English
ISSN :
03855643
Volume :
35
Issue :
1
Database :
OpenAIRE
Journal :
熱帯医学 Tropical medicine
Accession number :
edsair.jairo.........881fccecbcfc9a1b537a182028fdd1fe