A trial of web-based method to teach impact of genome variation on protein structures at high school

The advancement of genome sequencing technology has unveiled whole DNA sequences of individuals. Comparison of the genome sequences has uncovered differences among human population which may relate to the differences in the susceptibility to diseases of each person. The wisdom acquired by the stateof- the-art technology should be shared in the society, especially among the next generation to advance their quality of life. We developed an easy-to-use web interface to promote the idea of genome sequence variation, effect on protein structures and the relationship between the variations and diseases in humans. We used the web tool in the Super Science High School Program class and assessed the impact of using the tools for the promotion of understanding among high school pupils.