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CD7-Positive Diffuse Large B-Cell Lymphoma Presenting as an Intranasal Tumor

Authors :
Teshima, Kazuaki
Kume, Masaaki
Kawaharada, Yasushi
Saito, Takashi
Abe, Ko
Ikeda, Sho
Ohyagi, Hideaki
Zuguchi, Megumi
Zuguchi, Masashi
Kubota, Yosuke
Enomoto, Yoshitaka
Miura, Masahito
Takahashi, Satsuki
Saito, Masahiro
Saito, Ken
Takahashi, Naoto
Source :
Case Reports in Hematology.
Publication Year :
2020
Publisher :
Hindawi, 2020.

Abstract

We report a case of a 74-year-old man with a cluster of differentiation (CD) 7-positive diffuse large B-cell lymphoma (DLBCL) in the right nasal cavity. Flow cytometry analyses showed CD7 and CD20 positivity in tumor cells. The patient received 6 cycles of R-CHOP plus local radiation therapy because positron emission tomography-computed tomography after R-CHOP revealed an intranasal lesion. The patient achieved complete remission (CR) after radiation therapy. The frequency of CD7-positive DLBCL is rare, and only 11 cases with follow-up of clinical course have been reported thus far. CR or partial response was noted in 8 of 11 cases after receiving rituximab combined with chemotherapy. In total, 9 of 12 cases involved the development of extranodal lesions, which occurred as an intranasal tumor in 3 cases. It is important to examine the clinical features by accumulation of further cases.

Details

Language :
English
ISSN :
20906560
Database :
OpenAIRE
Journal :
Case Reports in Hematology
Accession number :
edsair.hindawi.publ..d63baa4c8fbf52585d9b030b94528244
Full Text :
https://doi.org/10.1155/2020/1514729