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CD7-Positive Diffuse Large B-Cell Lymphoma Presenting as an Intranasal Tumor
- Source :
- Case Reports in Hematology.
- Publication Year :
- 2020
- Publisher :
- Hindawi, 2020.
-
Abstract
- We report a case of a 74-year-old man with a cluster of differentiation (CD) 7-positive diffuse large B-cell lymphoma (DLBCL) in the right nasal cavity. Flow cytometry analyses showed CD7 and CD20 positivity in tumor cells. The patient received 6 cycles of R-CHOP plus local radiation therapy because positron emission tomography-computed tomography after R-CHOP revealed an intranasal lesion. The patient achieved complete remission (CR) after radiation therapy. The frequency of CD7-positive DLBCL is rare, and only 11 cases with follow-up of clinical course have been reported thus far. CR or partial response was noted in 8 of 11 cases after receiving rituximab combined with chemotherapy. In total, 9 of 12 cases involved the development of extranodal lesions, which occurred as an intranasal tumor in 3 cases. It is important to examine the clinical features by accumulation of further cases.
- Subjects :
- Article Subject
immune system diseases
hemic and lymphatic diseases
Subjects
Details
- Language :
- English
- ISSN :
- 20906560
- Database :
- OpenAIRE
- Journal :
- Case Reports in Hematology
- Accession number :
- edsair.hindawi.publ..d63baa4c8fbf52585d9b030b94528244
- Full Text :
- https://doi.org/10.1155/2020/1514729