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Electrospun Nanofibers Containing Strontium for Bone Tissue Engineering

Authors :
Zhang, Qi
Ji, Yanjing
Zheng, Weiping
Yan, Mingzhe
Wang, Danyang
Li, Min
Chen, Junbo
Yan, Xiao
Zhang, Qiang
Yuan, Xiao
Zhou, Qihui
Source :
Journal of Nanomaterials.
Publication Year :
2020
Publisher :
Hindawi, 2020.

Abstract

Electrospun polymer/metal composite nanofibers have received much attention in the field of bone tissue engineering and regenerative medicine (BTERM) owing to their extracellular matrix- (ECM-) like structure, sufficient mechanical strength, favorable biological properties, and bone induction. In particular, electrospun nanofibers containing strontium (Sr) can significantly promote bone repair and regeneration by mediating osteolysis and osteogenesis, which offers a promising bioactive material for BTERM. In this review, we summarized the effects of electrospun nanofibers containing Sr on stem cells, osteoblasts, and osteoclasts in BTERM. Also, current challenges and future perspectives for electrospun nanofibers containing Sr in BTERM are briefly outlined. It is hoped that the systematic overview will inspire the readers to further study Sr-containing nanofibers for BTERM and accelerate their translation from the bench to the clinic.

Details

Language :
English
ISSN :
16874110
Database :
OpenAIRE
Journal :
Journal of Nanomaterials
Accession number :
edsair.hindawi.publ..73c2481cdd5e57913bc661516adcf8a5
Full Text :
https://doi.org/10.1155/2020/1257646