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Incidence and outcomes of infective endocarditis following transcatheter aortic valve implantation

Authors :
Bernard Prendergast
Tiffany Patterson
Simon Redwood
Omar Chehab
Christopher Allen
Thomas J. Cahill
Source :
Expert Review of Cardiovascular Therapy. 18:653-662
Publication Year :
2020
Publisher :
Informa UK Limited, 2020.

Abstract

Prosthetic valve infective endocarditis is a feared and potentially catastrophic complication of valvular intervention. Transcatheter aortic valve implantation has transformed the modern management of aortic stenosis and vastly altered the demographics of those patients undergoing valve replacement.As a relatively nascent development, what TAVI means for the epidemiology of infective endocarditis, how to identify those patients undergoing the procedure at greatest risk, and how best to prevent and manage the condition remains the subject of fervent research activity. In this review, we appraise relevant contemporary data discussing the incidence, microbiological profiles, associated risk factors and clinical outcomes of infective endocarditis after TAVI.Present outcomes are poor, with exceedingly high in-hospital and long-term mortality. Evidence to support surgical management in this patient group is lacking. Prevention is therefore paramount and a logical focus for future research attention.

Details

ISSN :
17448344 and 14779072
Volume :
18
Database :
OpenAIRE
Journal :
Expert Review of Cardiovascular Therapy
Accession number :
edsair.doi.dedup.....ffa3434cdd23d99ec5e1e0b92f0f3bd9
Full Text :
https://doi.org/10.1080/14779072.2020.1839419