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Implementation of recommendations for the screening of hydroxychloroquine retinopathy: poor adherence of rheumatologists and ophthalmologists
- Source :
- Lupus. 26(3)
- Publication Year :
- 2016
-
Abstract
- The American Academy of Ophthalmology published in 2011 revised recommendations regarding screening for hydroxychloroquine (HCQ) toxicity. We aimed to assess implementation of these recommendations by rheumatologists and ophthalmologists. A questionnaire regarding screening practices for HCQ toxicity was distributed among all members of the Israeli societies of Rheumatology and Ophthalmology. A total of 128 physicians responded to the questionnaire (rheumatologists: 60, ophthalmologists: 68). Only 5% of the rheumatologists and 15% of the ophthalmologists are aware of ophthalmologic assessments recommended for baseline and follow-up evaluation. When an abnormal test is detected, even if inappropriate for HCQ toxicity screening, 60% of the responders recommend cessation of therapy. Only 13% of the responders recommend first follow-up after five years for patients without risk factors; the remainder recommend more frequent testing. Ninety-six percent of the responders are not aware of all of the known risk factors for HCQ toxicity. Use of inappropriate tests to detect HCQ retinal toxicity may lead to unnecessary cessation of beneficial treatment with risk of disease flare, while lack of consideration of risk factors may put patients at risk for toxicity. These results emphasize the importance of implementing the recommendations to ensure safe and effective use of this drug.
- Subjects :
- medicine.medical_specialty
Alternative medicine
Disease
Poor adherence
Arthritis, Rheumatoid
03 medical and health sciences
0302 clinical medicine
Rheumatology
Retinal Diseases
Risk Factors
Internal medicine
Surveys and Questionnaires
medicine
Humans
Lupus Erythematosus, Systemic
Mass Screening
Israel
Intensive care medicine
030203 arthritis & rheumatology
Ophthalmologists
business.industry
Hydroxychloroquine
medicine.disease
Retinal toxicity
Antirheumatic Agents
Practice Guidelines as Topic
030221 ophthalmology & optometry
Physical therapy
Guideline Adherence
Rheumatologists
business
Retinopathy
medicine.drug
Subjects
Details
- ISSN :
- 14770962
- Volume :
- 26
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Lupus
- Accession number :
- edsair.doi.dedup.....ff9cccdfb44c2f39a3da85c25213ebbb