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Flexible Organic Framework-Based Anthracycline Prodrugs for Enhanced Tumor Growth Inhibition
- Source :
- ACS applied bio materials. 4(5)
- Publication Year :
- 2022
-
Abstract
- A water-soluble flexible organic framework FOF-hz of low cytotoxicity has been synthesized from a pyridinium-derived tetracationic tetraaldehyde and a citric acid-derived tritopic acylhydrazine (1:...
- Subjects :
- Anthracycline
Biomedical Engineering
Hydrazone
Antineoplastic Agents
Biocompatible Materials
Biomaterials
chemistry.chemical_compound
Materials Testing
Humans
Anthracyclines
Prodrugs
Particle Size
Cytotoxicity
Cell Proliferation
Antitumor activity
chemistry.chemical_classification
Biochemistry (medical)
Acylhydrazine
Dynamic covalent chemistry
General Chemistry
Prodrug
Combinatorial chemistry
chemistry
MCF-7 Cells
Tumor growth inhibition
Drug Screening Assays, Antitumor
Subjects
Details
- ISSN :
- 25766422
- Volume :
- 4
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- ACS applied bio materials
- Accession number :
- edsair.doi.dedup.....ff9abd3e04556722b872494d433094d3