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Neurofibromatosis, stroke and basilar impression: case report
- Source :
- Arquivos de Neuro-Psiquiatria, Vol 57, Iss 2B, Pp 484-488 (1999)
- Publication Year :
- 1999
- Publisher :
- FapUNIFESP (SciELO), 1999.
-
Abstract
- Neurofibromatosis type 1 (NF1) can virtually affect any organ, presenting most frequently with "cafe au lait" spots and neurofibromas. Vasculopathy is a known complication of NF1, but cerebrovascular disease is rare. We report the case of a 51-year-old man admitted to the hospital with a history of stroke four months before admission. On physical examination, he presented various "cafe au lait" spots and cutaneous neurofibromas. Neurologic examination demonstrated right-sided facial paralysis, right-sided hemiplegia, and aphasia. Computed tomography scan of head showed hypodense areas in the basal ganglia and centrum semiovale. Radiographs of cranium and cervical spine showed basilar impression. Angiography revealed complete occlusion of both vertebral and left internal carotid arteries, and partial stenosis of the right internal carotid artery. A large network of collateral vessels was present (moyamoya syndrome). It is an uncommon case of occlusive cerebrovascular disease associated with NF1, since most cases described in the literature are in young people, and tend to spare the posterior cerebral circulation. Basilar impression associated with this case may be considered a pure coincidence, but rare cases of basilar impression and NF1 have been described.
- Subjects :
- Male
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Neurofibromatosis 1
basilar impression
Neurosciences. Biological psychiatry. Neuropsychiatry
Physical examination
Platybasia
Centrum semiovale
Humans
Medicine
Moyamoya disease
Neurofibromatosis
Stroke
neurofibromatosis
medicine.diagnostic_test
moyamoya syndrome
business.industry
Syndrome
Middle Aged
medicine.disease
stroke
Facial paralysis
Surgery
Cerebrovascular Disorders
Neurology
Angiography
Neurology (clinical)
Radiology
Moyamoya Disease
business
RC321-571
Subjects
Details
- ISSN :
- 0004282X
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- Arquivos de Neuro-Psiquiatria
- Accession number :
- edsair.doi.dedup.....ff5ac0565a61397f59cd6b027825beba