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Compounds fromArnebia euchromaand Their Related Anti-HCV and Antibacterial Activities
- Source :
- Planta Medica. 78:39-45
- Publication Year :
- 2011
- Publisher :
- Georg Thieme Verlag KG, 2011.
-
Abstract
- Three new hydroquinone terpenoids with benzogeijerene skeletons, euchroquinols A-C (1- 3), and a new monoterpenylbenzenoid, 9,17-epoxyarnebinol (4), along with five known compounds were isolated from the stem bark of ARNEBIA EUCHROMA. Shikonin (6) exhibited potent anti-HCV activity with a selective index of 43.56, and compounds 1, 6, and des-O-methyllasiodiplodin (7) showed anti-Staphylococcus aureus activity with MICs of 0.5, 0.125, and 0.125 mg/mL, respectively.
- Subjects :
- Staphylococcus aureus
Arnebia euchroma
Pharmaceutical Science
Hepacivirus
Microbial Sensitivity Tests
Antiviral Agents
Analytical Chemistry
chemistry.chemical_compound
Drug Discovery
Botany
Plant Bark
Pharmacology
Stem bark
Plant Stems
Hydroquinone
biology
Traditional medicine
Plant Extracts
Anti hiv
Organic Chemistry
Boraginaceae
biology.organism_classification
Terpenoid
Anti-Bacterial Agents
Complementary and alternative medicine
chemistry
Molecular Medicine
Antibacterial activity
Naphthoquinones
Subjects
Details
- ISSN :
- 14390221 and 00320943
- Volume :
- 78
- Database :
- OpenAIRE
- Journal :
- Planta Medica
- Accession number :
- edsair.doi.dedup.....ff300b1595134e8aed109493d3ee3450