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Does the Combined Effect of Resistance Training with EPO and Iron Sulfate Improve Iron Metabolism in Older Individuals with End-Stage Renal Disease?
- Source :
- Nutrients, Volume 13, Issue 9, Nutrients, Vol 13, Iss 3250, p 3250 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- We sought to investigate the effects of resistance training (RT) combined with erythropoietin (EPO) and iron sulfate on the hemoglobin, hepcidin, ferritin, iron status, and inflammatory profile in older individuals with end-stage renal disease (ESRD). ESRD patients (n: 157<br />age: 66.8 ± 3.6<br />body mass: 73 ± 15<br />body mass index: 27 ± 3), were assigned to control (CTL<br />n: 76) and exercise groups (RT<br />n: 81). The CTL group was divided according to the iron treatment received: without iron treatment (CTL—none<br />n = 19), treated only with iron sulfate or EPO (CTL—EPO or IRON<br />n = 19), and treated with both iron sulfate and EPO (CTL—EPO + IRON<br />n = 76). The RT group followed the same pattern: (RT—none<br />n = 20), (RT—EPO or IRON<br />n = 18), and (RT—EPO + IRON<br />n = 86). RT consisted of 24 weeks/3 days per week at moderate intensity of full-body resistance exercises prior to the hemodialysis section. The RT group, regardless of the iron treatment, improved iron metabolism in older individuals with ESRD. These results provide some clues on the effects of RT and its combination with EPO and iron sulfate in this population, highlighting RT as an important coadjutant in ESRD-iron deficiency.
- Subjects :
- medicine.medical_specialty
Anemia
Iron
Population
nephrology
urologic and male genital diseases
Gastroenterology
Article
End stage renal disease
chemistry.chemical_compound
Hemoglobins
Hepcidins
Hepcidin
Internal medicine
hemic and lymphatic diseases
medicine
Humans
TX341-641
iron metabolism
Ferrous Compounds
education
Aged
Inflammation
education.field_of_study
Nutrition and Dietetics
biology
business.industry
Nutrition. Foods and food supply
Resistance Training
Middle Aged
medicine.disease
anemia
female genital diseases and pregnancy complications
Ferritin
Iron sulfate
chemistry
Erythropoietin
Ferritins
biology.protein
Kidney Failure, Chronic
Hemoglobin
hepcidin
erythropoietin
business
exercise training
chronic kidney disease
Food Science
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 20726643
- Database :
- OpenAIRE
- Journal :
- Nutrients
- Accession number :
- edsair.doi.dedup.....feeb9bc9597a36bd8c1f3e32ba5ffdb8
- Full Text :
- https://doi.org/10.3390/nu13093250