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Invasive Fungal Infections in Acute Promyelocytic Leukemia on Dual Differentiating Agents: Real World Data
Invasive Fungal Infections in Acute Promyelocytic Leukemia on Dual Differentiating Agents: Real World Data
- Source :
- Indian journal of hematologyblood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion. 34(3)
- Publication Year :
- 2017
-
Abstract
- Invasive fungal infection (IFI) in patients with acute promyelocytic leukemia (APL) is a common phenomenon in developing countries. In a systematic study (Dual Inducing Differentiating agents—Indian Trial: DID-IT) using dual differentiating agents (ATO and ATRA) in 98 APL patients at our center we report 18.3% incidence of IFI (n-18). Among all cases of IFI three were definitive, 14 were probable and one was possible IFI. We conclude that incidence of IFI in APL is affected by environmental and therapy related factors and mere usage of dual differentiating agents need not necessarily decrease the incidence of fungal infections.
- Subjects :
- Oncology
Acute promyelocytic leukemia
medicine.medical_specialty
Pathology
Hematology
Therapy related
business.industry
Incidence (epidemiology)
Short Communication
medicine.disease
03 medical and health sciences
0302 clinical medicine
Differentiating Agents
030220 oncology & carcinogenesis
Internal medicine
medicine
In patient
business
Real world data
neoplasms
030215 immunology
Subjects
Details
- ISSN :
- 09714502
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Indian journal of hematologyblood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
- Accession number :
- edsair.doi.dedup.....fe813db509e73f24e22a4be25af357f9