Back to Search
Start Over
Functional hierarchy of oculomotor and visual motion subnetworks within the human cortical optokinetic system
- Source :
- Brain Structure and Function. 224:567-582
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Optokinetic look nystagmus (look OKN) is known to engage cortical visual motion and oculomotor hubs. Their functional network hierarchy, however, and the role of the cingulate eye field (CEF) and the dorsolateral prefrontal cortex (DLPFC) in particular have not been investigated. We used look OKN in fMRI to identify all cortical visual motion and oculomotor hubs involved. Using these activations as seed regions, we employed hierarchical clustering in two differing resting state conditions from a separate public data set. Robust activations in the CEF highlight its functional role in OKN and involvement in higher order oculomotor control. Deactivation patterns indicate a decreased modulatory involvement of the DLPFC. The hierarchical clustering revealed a changeable organization of the eye fields, hMT, V3A, and V6 depending on the resting state condition, segregating executive from higher order visual subnetworks. Overall, hierarchical clustering seems to allow for a robust delineation of physiological cortical networks.
- Subjects :
- Adult
Male
Histology
Computer science
Motion Perception
Nystagmus
050105 experimental psychology
Functional networks
Young Adult
03 medical and health sciences
0302 clinical medicine
Neural Pathways
medicine
Humans
0501 psychology and cognitive sciences
Nystagmus, Optokinetic
Cerebral Cortex
Brain Mapping
Resting state fMRI
Hierarchy (mathematics)
General Neuroscience
05 social sciences
Optokinetic reflex
Magnetic Resonance Imaging
Visual motion
Hierarchical clustering
Dorsolateral prefrontal cortex
medicine.anatomical_structure
Visual Perception
Female
Nerve Net
Anatomy
medicine.symptom
Neuroscience
Photic Stimulation
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 18632661 and 18632653
- Volume :
- 224
- Database :
- OpenAIRE
- Journal :
- Brain Structure and Function
- Accession number :
- edsair.doi.dedup.....fe4d437bbda6ec2f22ad238119504d18