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Interactions of PIN and PGP auxin transport mechanisms
- Source :
- ResearcherID
- Publication Year :
- 2007
- Publisher :
- Portland Press Ltd., 2007.
-
Abstract
- Polarized transport of the plant hormone auxin influences multiple growth processes in plants and is regulated by plasma-membrane-localized efflux and uptake carriers. The PGP (P-glycoprotein) ABC transporters (ATP-binding-cassette transporters), PIN (pin-formed) subfamily of major facilitator proteins and members of AUX/LAX families have been shown to independently transport auxin both in planta and in heterologous systems. However, PIN- and PGP-mediated transport in heterologous systems exhibits decreased substrate specificity and inhibitor-sensitivity compared with what is seen in plants and plant cells. To determine whether PIN–PGP interactions enhance transport specificity, we analysed interactions of the representative auxin-transporting PGPs with PIN1 and AUX1 in planta and in heterologous systems. Here, we provide evidence that PINs and PGPs interact and function both independently and co-ordinately to control polar auxin transport and impart transport specificity and directionality. These interactions take place in protein complexes stabilized by PGPs in detergent-resistant microdomains.
- Subjects :
- Light
Arabidopsis
Heterologous
ATP-binding cassette transporter
Models, Biological
Biochemistry
Plant Growth Regulators
Gene Expression Regulation, Plant
Auxin
Plant Physiological Phenomena
chemistry.chemical_classification
Indoleacetic Acids
biology
Arabidopsis Proteins
fungi
Membrane Transport Proteins
food and beverages
Biological Transport
Transporter
biology.organism_classification
Cell biology
chemistry
ATP-Binding Cassette Transporters
Efflux
Plant hormone
Polar auxin transport
Subjects
Details
- ISSN :
- 14708752 and 03005127
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Biochemical Society Transactions
- Accession number :
- edsair.doi.dedup.....fe32c1f116abaaccc96766028b3ebbe5
- Full Text :
- https://doi.org/10.1042/bst0350137