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Risk of Mortality in Association with Pregnancy in Women Following Motor Vehicle Crashes: A Systematic Review and Meta-Analysis

Authors :
Ya-Hui Chang
Ya-Yun Cheng
Wen-Hsuan Hou
Yu-Wen Chien
Chiung-Hsin Chang
Ping-Ling Chen
Tsung-Hsueh Lu
Lucia Yovita Hendrati
Chung-Yi Li
Ning-Ping Foo
Source :
International Journal of Environmental Research and Public Health, Vol 19, Iss 911, p 911 (2022), International Journal of Environmental Research and Public Health
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

The aim of the study was to provide a systematic review and meta-analysis of studies examining the association between mortality risk and motor vehicle crashes (MVCs) in pregnant women compared with nonpregnant women. We used relevant MeSH terms to identify epidemiological studies of mortality risk in relation to MVCs from PubMed, Embase, and MEDLINE databases. The Newcastle–Ottawa Scale (NOS) was used for quality assessment. For comparison of mortality from MVCs between pregnant and nonpregnant women, the pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using a random effects model. The eight studies selected met all inclusion criteria. These studies included 14,120 injured victims who were pregnant at the time of the incident and 207,935 victims who were not pregnant. Compared with nonpregnant women, pregnant women had a moderate but insignificant decrease in mortality risk (pooled OR = 0.68, 95% CI = 0.38–1.22, I2 = 88.71%). Subgroup analysis revealed that the pooled OR significantly increased at 1.64 (95% CI = 1.16–2.33, I2 < 0.01%) for two studies with a similar difference in the mean injury severity score (ISS) between pregnant and nonpregnant women. Future studies should further explore the risk factors associated with MVCs in pregnant women to reduce maternal mortality.

Details

Language :
English
ISSN :
16617827 and 16604601
Volume :
19
Issue :
911
Database :
OpenAIRE
Journal :
International Journal of Environmental Research and Public Health
Accession number :
edsair.doi.dedup.....fe2fa906b1941bb23f6446b487aa9b01