Back to Search
Start Over
Fetal cells in the blood of pregnant women: detection and enrichment by fluorescence-activated cell sorting
- Source :
- Proceedings of the National Academy of Sciences of the United States of America. 76(3)
- Publication Year :
- 1979
-
Abstract
- Fetal cells, potentially usable for prenatal diagnosis, were sorted from maternal blood samples taken as early as 15 weeks of gestation. Immunogenetic and cytogenic criteria established the fetal origin of the observed cells: Y-chromatin-containing (male) cells were detected in the sorted sample if and only if the newborn proved to be male and carried cell-surface antigens detected by the fluorescent-labeled antibody used for sorting with the fluorescence-activated cell sorter.
- Subjects :
- Male
Prenatal diagnosis
Gestational Age
Human leukocyte antigen
Cell Separation
Andrology
Fetus
Antigen
HLA Antigens
Pregnancy
Prenatal Diagnosis
Y Chromosome
medicine
Humans
Multidisciplinary
biology
Gestational age
medicine.disease
Blood
Microscopy, Fluorescence
Immunology
biology.protein
Gestation
Female
Antibody
Research Article
Subjects
Details
- ISSN :
- 00278424
- Volume :
- 76
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Accession number :
- edsair.doi.dedup.....fde8c9cd618b2b332e31f7bffcd6a021