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Validity of procalcitonin for the diagnosis of bacterial infection in elderly patients
- Source :
- Enfermedades infecciosas y microbiologia clinica. 33(8)
- Publication Year :
- 2014
-
Abstract
- Introduction PCT has been consolidated as a key tool in the diagnosis of bacterial infections in general population. Few studies have been conducted to determine the applicability of this test in elderly patients. Methods Study of validity of PCT on elderly patients. Two groups were formed; the first group was formed by patients aged 75 years or older, under bacterial infection criteria and PCT on the initial Lab test. The second group was formed by patients aged 75 years or older with any noninfectious disease; these patients were asked PCT in the initial Lab test. Sensitivity, specificity, positive and negative likelihood ratio were calculated. Results 161 patients were included, 95 with probable bacterial infection and 66 without infection. Patients with probable bacterial infection criteria, 72% of them had PCT >0.5 ng/mL. Patients without infection, 8% of the patients had PCT >0.5 ng/mL. Sensitivity and specificity of PCT to bacterial infection with the cutoff value of 0.5 ng/mL was 72% and 92%, respectively. Conclusion PCT can be used in elderly patients to diagnose bacterial infections because it has proved good sensitivity and high specificity.
- Subjects :
- Microbiology (medical)
Calcitonin
Male
medicine.medical_specialty
Population
Comorbidity
Sensitivity and Specificity
Procalcitonin
Predictive Value of Tests
Internal medicine
Sepsis
parasitic diseases
medicine
Diabetes Mellitus
Humans
Prospective Studies
Renal Insufficiency, Chronic
education
Aged
Retrospective Studies
Aged, 80 and over
education.field_of_study
Likelihood Functions
business.industry
Bacterial Infections
bacterial infections and mycoses
Surgery
Female
Nervous System Diseases
business
hormones, hormone substitutes, and hormone antagonists
Biomarkers
Subjects
Details
- ISSN :
- 15781852
- Volume :
- 33
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Enfermedades infecciosas y microbiologia clinica
- Accession number :
- edsair.doi.dedup.....fd7bb8684dffbee8ee35011a7804a7f4