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Accuracy of Foot Pressure Measurement on Predicting the Development of Foot Ulcer in Patients with Diabetes: A Systematic Review and Meta-Analysis
- Source :
- J Diabetes Sci Technol
- Publication Year :
- 2021
- Publisher :
- SAGE Publications, 2021.
-
Abstract
- Objective: Areas of the foot with diabetic ulcers have been observed to have greater plantar pressures compared to non-ulcerated. Pressures play an essential role in the mechanism of lesion, and their reduction is effective in prevention. We conducted a systematic review to evaluate pedobarography as a predictive tool for ulcer development, since there is still no consensus on this aspect. Methods: We searched PUBMED (MedLine), EMBASE, Scopus, Web of Science, CINAHL and Scielo for cohort studies that measured plantar pressure at baseline and verified ulcer development on follow-up. Pooled effects of accuracy, sensitivity, specificity and relative risk were calculated using the inverse variance method. Risk of bias was assessed using the QUADAS-2 tool. Results: Three studies ( n = 2000) had enough information on accuracy to be included into a meta-analysis, and 4 ( n = 2651) were analyzed using qualitative methods. Pooled sensitivity and specificity were found to be 0.63 (Confidence Interval (CI) 0.58-0.68) and 0.42 (CI 0.27-0.58), respectively. Pooled relative risk was 1.95 (CI 1.09-3.51). Risk of bias was low to uncertain. Conclusions: Pedobarography in itself appears to have low accuracy in evaluating risk of ulceration. Several methodological heterogeneities were found, and the most optimal cut-off value is yet to be determined.
- Subjects :
- medicine.medical_specialty
business.industry
Special Section: Diabetic Foot Ulcer Technology
Endocrinology, Diabetes and Metabolism
Biomedical Engineering
MEDLINE
Bioengineering
CINAHL
medicine.disease
Confidence interval
Meta-analysis
Internal medicine
Relative risk
Diabetes mellitus
Internal Medicine
medicine
Pedobarography
business
Cohort study
Subjects
Details
- ISSN :
- 19322968
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Journal of Diabetes Science and Technology
- Accession number :
- edsair.doi.dedup.....fd7303a76289ee5e26181b13838ac652