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Reprograming immunity to food allergens
- Source :
- Journal of Allergy and Clinical Immunology. 141:1936-1939.e2
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- A novel immune-modulatory therapy utilizing targeted delivery of cytokines to draining lymph nodes effectively reprograms Th2 allergic responses towards a Th1 and tolerogenic profile, resulting in protection from peanut antigen-induced anaphylaxis.
- Subjects :
- Immunology
02 engineering and technology
010402 general chemistry
01 natural sciences
Article
Mice
Th2 Cells
Immunity
medicine
Animals
Humans
Immunology and Allergy
Food allergens
Extramural
business.industry
Allergens
Th1 Cells
021001 nanoscience & nanotechnology
medicine.disease
0104 chemical sciences
Mice, Inbred C57BL
Food
Female
Immunotherapy
Lymph
0210 nano-technology
business
Food Hypersensitivity
Anaphylaxis
Subjects
Details
- ISSN :
- 00916749
- Volume :
- 141
- Database :
- OpenAIRE
- Journal :
- Journal of Allergy and Clinical Immunology
- Accession number :
- edsair.doi.dedup.....fd6174bb0ae9c6f3d4444d67fa1fe79f
- Full Text :
- https://doi.org/10.1016/j.jaci.2018.01.020