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Nonalcoholic fatty liver disease: a frequent condition in type 2 diabetic patients

Authors :
Mihaela Rosu
Roxana Sirli
Alexandra Sima
Adrian Vlad
Alina Popescu
Romulus Timar
Bogdan Timar
Isabel Dan
Ioan Sporea
Source :
Wiener klinische Wochenschrift. 126:335-340
Publication Year :
2014
Publisher :
Springer Science and Business Media LLC, 2014.

Abstract

Nonalcoholic fatty liver disease represents an excessive fat accumulation in the liver of patients with no other liver disease and no history of alcohol abuse. It is associated with insulin resistance, being more prevalent in obesity and type 2 diabetes. Our aim was to assess the prevalence of fatty liver and nonalcoholic steatohepatitis in patients with type 2 diabetes and to evaluate the influence of obesity on its prevalence. We included 348 type 2 diabetes patients (age: 18–65 years), without a history of liver disease or alcohol abuse. We assessed demographical data, medical history, physical examination, blood tests, and abdominal ultrasonography. The prevalence of liver steatosis in our group was 87.1 %, with no significant differences between men and women. Patients with steatosis had higher abdominal circumference, body mass index (BMI; p = 0.001), and serum triglyceride (p

Details

ISSN :
16137671 and 00435325
Volume :
126
Database :
OpenAIRE
Journal :
Wiener klinische Wochenschrift
Accession number :
edsair.doi.dedup.....fd3a1978cb7e9205d0fcfe1853b5aa66