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An In Vivo Study to Evaluate the Efficacy of Blue Shark (Prionace glauca) Cartilage Collagen as a Cosmetic

Authors :
Wen-Chien Lu
Chien-Shan Chiu
Yung-Jia Chan
Tian-Pin Guo
Ching-Chin Lin
Po-Chun Wang
Po-Yu Lin
Amanda Tresiliana Mulio
Po-Hsien Li
Source :
Marine Drugs; Volume 20; Issue 10; Pages: 633
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

The “blue shark”, Prionace glauca (class: Chondrichthyes), is a pelagic shark species commonly found in tropical and temperate oceans. This shark is mainly sold in Asian countries as food and as traditional Chinese medicine. According to the Red List of the International Union for the Conservation of Nature, P. glauca is classified as low-risk to near endangered. P. glauca cartilage contains collagen type II, which makes it suitable as a bioactive ingredient in cosmeceutical products. This study evaluated the effects of a gel containing various concentrations (0.125–5%) of lyophilized hydrolyzed P. glauca cartilage on the human inner wrist skin compared to a placebo (base). A skin properties evaluation test was conducted before and after applying various concentrations (0.125–5%) of the P. glauca cartilage gel for 10 and 20 min on the inner wrists of participants using a skin analyzer that determined the moisture level, oil level, texture level, complexion level, and the 3D level. Adding lyophilized hydrolyzed shark cartilage (LHSC) significantly improved the moisture, texture, and complexion of the skin while controlling oil and providing a wrinkle-smoothing effect. The result indicated that LHSC formulations were prepared at different concentrations, and they had significantly enhanced effects on skin hydration and elasticity (texture) and the smoothing of wrinkles (3D level). The LHSC also effectively controlled oil secretion and the complexion.

Details

ISSN :
16603397
Volume :
20
Database :
OpenAIRE
Journal :
Marine Drugs
Accession number :
edsair.doi.dedup.....fd360a08c2fd97635b69c0f19f9dfa7c
Full Text :
https://doi.org/10.3390/md20100633