Detecting a major gene in an F2 population

Authors :: G. Montes De Oca
Patrice Loisel
Bruno Goffinet
Hervé Monod
Unité de Biométrie et Intelligence Artificielle (UBIA)
Institut National de la Recherche Agronomique (INRA)
Unité de recherche Biométrie (UB)
Source :: Biometrics, Biometrics, Wiley, 1994, 50, pp.512-516
Publication Year :: 1994
Publisher :: HAL CCSD, 1994.
Abstract: The aim of this paper is to study the behavior of the likelihood ratio test for the detection of a major gene in an F2 population. The model is a mixture of three normal distributions where the proportions are known. The information matrix is not positive definite, and therefore classical results cannot be used. An example concerning beans is given.

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