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Solid-Supported Lipid Multilayers under High Hydrostatic Pressure
- Source :
- Langmuir. 32:2638-2643
- Publication Year :
- 2016
- Publisher :
- American Chemical Society (ACS), 2016.
-
Abstract
- In this work, the structure of solid-supported lipid multilayers exposed to increased hydrostatic pressure was studied in situ by X-ray reflectometry at the solid-liquid interface between silicon and an aqueous buffer solution. The layers' vertical structure was analyzed up to a maximum pressure of 4500 bar. The multilayers showed phase transitions from the fluid into different gel phases. With increasing pressure, a gradual filling of the sublayers between the hydrophilic head groups with water was observed. This process was inverted when the pressure was decreased, yielding finally smaller water layers than those in the initial state. As is commonly known, water has an abrasive effect on lipid multilayers by the formation of vesicles. We show that increasing pressure can reverse this process so that a controlled switching between multi- and bilayers is possible.
- Subjects :
- 0301 basic medicine
Silicon
030103 biophysics
Phase transition
Materials science
Lipid Bilayers
Hydrostatic pressure
Analytical chemistry
chemistry.chemical_element
02 engineering and technology
Phase Transition
03 medical and health sciences
Hydrostatic Pressure
Electrochemistry
General Materials Science
Lipid bilayer
Reflectometry
Spectroscopy
Vesicle
Water
Surfaces and Interfaces
021001 nanoscience & nanotechnology
Condensed Matter Physics
chemistry
Chemical engineering
Head (vessel)
Dimyristoylphosphatidylcholine
0210 nano-technology
Bar (unit)
Subjects
Details
- ISSN :
- 15205827 and 07437463
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Langmuir
- Accession number :
- edsair.doi.dedup.....fd316616b07be01b5e3c46ea609aac0c