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Negative-pressure wound therapy for III/IV pressure injuries: A meta-analysis
- Source :
- Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyREFERENCES. 29(1)
- Publication Year :
- 2020
-
Abstract
- This meta-analysis was conducted to identify the potential benefits and the efficacy of negative-pressure wound therapy (NPWT) for III/IV pressure injuries (PIs) compared with standard wound care (SWC). Sixteen RCTs with 629 patients were included in our analysis. The methodological quality was assessed by the Cochrane Collaboration Tool. The outcomes included complete ulcer healing rate, wound healing time, pain score, the frequency of dressing change, hospitalization cost, the condition of the exudate, and the wound improvement. The percentage of healing rate was 61.45% for the NPWT group and 36.90% for SWC (95% CI: 1.32-1.70). There were significant differences in wound healing time (WMD = -16.47 days, 95% [CI (-22.36, - 10.59) days, P ≤ .001]). The pain score and hospitalization cost in NPWT was lower compared with SWC group (WMD = -2.39, 95% CI [-3.47, -1.30], P ≤ .001); (SMD = -2.55, 95% CI [-4.07, -1.03], P < .01). The frequency of dressing change in both NPWT groups was greatly reduced (SMD = -3.61, 95% [CI (-4.57, - 2.66) times, P ≤ .001]). Our meta-analysis indicated that NPWT was associated with greater improvements in improving PIs and shorting healing time for III/IV PIs. However, this conclusion needs to be confirmed by high-quality multicenter RCTs.
- Subjects :
- Ulcer healing
Pressure Ulcer
Pain score
Wound Healing
Wound therapy
business.industry
medicine.medical_treatment
Healing time
Dermatology
Severity of Illness Index
Dressing change
030207 dermatology & venereal diseases
03 medical and health sciences
Wound care
0302 clinical medicine
Anesthesia
Meta-analysis
Negative-pressure wound therapy
Medicine
Humans
Surgery
business
Negative-Pressure Wound Therapy
Subjects
Details
- ISSN :
- 1524475X
- Volume :
- 29
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyREFERENCES
- Accession number :
- edsair.doi.dedup.....fd26ff6bfff913df1f228e324f427598