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Coronary angioscopic findings 9 months after everolimus-eluting stent implantation compared with sirolimus-eluting stents
- Source :
- Journal of Cardiology. 61(1):22-30
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- ObjectivesWe assessed angioscopic findings after everolimus-eluting stents (EES) implantation, compared with sirolimus-eluting stents (SES).BackgroundCoronary angioscopy (CAS) provides an opportunity to assess neointimal coverage over stent struts, thrombus, and plaque color by direct visualization. CAS is a useful tool for evaluating stent struts after drug-eluting stent implantation. Angioscopic findings after EES implantation have not been reported before.MethodsWe performed CAS in 23 patients who were treated with EES and 41 patients with SES. CAS was performed 8.5 months after stent implantation. We assessed neointimal coverage, thrombus, and plaque color. We classified neointimal coverage in 4 grades: grade 0=struts were completely exposed; grade 1=struts were visible with dull light reflexion; grade 2=there was no light reflexion from slightly visible struts; grade 3=struts were completely covered.ResultsThere was no significant difference in minimum, maximum, dominant grade of neointimal coverage, and heterogeneity index between EES and SES. Thrombus was less frequently observed in EES than SES (4% vs 29%, p=0.02). When we divided study patients into acute coronary syndrome (ACS) or stable angina pectoris (SAP), there was a tendency toward less thrombus in EES than SES, in both ACS and SAP. Maximum color grade of the plaques was less advanced in EES than SES (p
- Subjects :
- Male
medicine.medical_specialty
Acute coronary syndrome
Time Factors
medicine.medical_treatment
Angioscopy
Coronary Artery Disease
Coronary artery disease
Percutaneous Coronary Intervention
Angioplasty
Internal medicine
Stent
medicine
Humans
Everolimus
cardiovascular diseases
Angioplasty, Balloon, Coronary
Thrombus
Aged
Sirolimus
medicine.diagnostic_test
Angioscopes
business.industry
Coronary Thrombosis
Percutaneous coronary intervention
Drug-Eluting Stents
Middle Aged
equipment and supplies
medicine.disease
Coronary Vessels
surgical procedures, operative
cardiovascular system
Cardiology
Female
business
Cardiology and Cardiovascular Medicine
medicine.drug
Subjects
Details
- ISSN :
- 09145087
- Volume :
- 61
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiology
- Accession number :
- edsair.doi.dedup.....fce95513ba6b83db733ad3bd92d9e269
- Full Text :
- https://doi.org/10.1016/j.jjcc.2012.08.011