Back to Search
Start Over
Fabrication techniques for microfluidic paper-based analytical devices and their applications for biological testing: A review
- Source :
- Biosensors and Bioelectronics. 77:774-789
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Paper is increasingly recognized as a user-friendly and ubiquitous substrate for construction of microfluidic devices. Microfluidic paper-based analytical devices (μPADs) provide an alternative technology for development of affordable, portable, disposable and low-cost diagnostic tools for improving point of care testing (POCT) and disease screening in the developing world, especially in those countries with no- or low-infrastructure and limited trained medical and health professionals. We in this review present fabrication techniques for microfluidic devices and their respective applications for biological detection as reported to date. These include: (i) fabrication techniques: examples of devices fabricated by using two-dimensional (2D) and three-dimensional (3D) methods; (ii) detection application: biochemical, immunological and molecular detection by incorporating efficient detection methods such as, colorimetric detection, electrochemical detection, fluorescence detection, chemiluminescence (CL) detection, electrochemiluninescence (ECL) detection, photoelectrochemi (PEC) detection and so on. In addition, main advantages, disadvantages and future trends for the devices are also discussed in this review.
- Subjects :
- Paper
Fabrication
Computer science
Point-of-Care Systems
Point-of-care testing
Microfluidics
Biomedical Engineering
Biophysics
Nanotechnology
Biosensing Techniques
02 engineering and technology
Electrochemical detection
Diagnostic tools
Sensitivity and Specificity
01 natural sciences
Biological Testing
Lab-On-A-Chip Devices
Electrochemistry
Disposable Equipment
Immunoassay
Health professionals
010401 analytical chemistry
Reproducibility of Results
Equipment Design
General Medicine
Paper based
021001 nanoscience & nanotechnology
0104 chemical sciences
Equipment Failure Analysis
0210 nano-technology
Biotechnology
Subjects
Details
- ISSN :
- 09565663
- Volume :
- 77
- Database :
- OpenAIRE
- Journal :
- Biosensors and Bioelectronics
- Accession number :
- edsair.doi.dedup.....fce866c18bd955650db91751066fbb83