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Long-term recurrence-free survival of a patient with advanced pure primary ovarian squamous cell carcinoma treated with dose-dense paclitaxel combined with carboplatin
- Source :
- Obstetrics & Gynecology Science
- Publication Year :
- 2017
- Publisher :
- Korean Society of Obstetrics and Gynecology, 2017.
-
Abstract
- We describe an extremely rare case of advanced pure primary ovarian squamous cell carcinoma (SCC), treated by adjuvant chemotherapy with dose-dense paclitaxel combined with carboplatin (dd-TC) plus the combination chemotherapy with irinotecan and cisplatin (CPT-P), with long-term recurrence-free survival. A 71-year-old woman complaining of lower abdominal pain was referred to our hospital and a 7-cm-diameter solid tumor was identified. She was diagnosed with a left ovarian tumor that was highly suspicious for malignancy based on ultrasonography, magnetic resonance imaging, and contrast-enhanced computed tomography. Bilateral salpingo-oophorectomy, low-anterior colon resection, and colostomy were performed. Intra- and post-operative histopathological diagnosis revealed International Federation of Gynecology and Obstetrics stage IIIc well-differentiated pure ovarian SCC. As adjuvant chemotherapy, 2 courses of dd-TC were administered, followed by 3 courses of CPT-P; the patient then underwent 4 additional courses of dd-TC. Both regimens were effective and there has been no recurrence or metastasis thus far in the 5 years since the operation.
- Subjects :
- Oncology
medicine.medical_specialty
Paclitaxel
Case Report
Ovarian neoplasms
Carboplatin
Metastasis
03 medical and health sciences
Ovarian tumor
chemistry.chemical_compound
0302 clinical medicine
Dose-dense therapy
Squamous cell carcinoma
Internal medicine
medicine
Stage IIIC
030212 general & internal medicine
Ovarian Squamous Cell Carcinoma
Cisplatin
business.industry
Obstetrics and Gynecology
Combination chemotherapy
Gynecologic Oncology
medicine.disease
Irinotecan
chemistry
030220 oncology & carcinogenesis
Radiology
business
medicine.drug
Subjects
Details
- ISSN :
- 22878580 and 22878572
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Obstetrics & Gynecology Science
- Accession number :
- edsair.doi.dedup.....fc90ede8d5c98564498d2edce9abdc37