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Domino Palladium(II)-Mediated Rearrangement-Oxidative Cyclization of β-Aminocyclopropanols

Authors :
Alessandra Zanobini
Stefano Cicchi
Matteo Betti
Alberto Brandi
Julia Revuelta
Source :
Scopus-Elsevier

Abstract

β-Aminocyclopropanols were transformed, in a domino process catalyzed by Pd(II) salts, into the corresponding 2,3-dihydro-lH-pyridin-4-ones. Conversely the use of a Pd(0) derivative, Pd(dba) 2 , afforded the corresponding tetrahydropyrid-4-ones. The saturated derivatives were also obtained, in better yields, using Pd(II) and Cu(OAc) 2 as stoichiometric oxidant.

Details

Database :
OpenAIRE
Journal :
Scopus-Elsevier
Accession number :
edsair.doi.dedup.....fc608382387f7a538c4c78732bc7edda