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Dried blood spot compared to plasma measurements of blood-based biomarkers of brain injury in neonatal encephalopathy
- Source :
- Pediatric Research. 85:655-661
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Data correlating dried blood spots (DBS) and plasma concentrations for neonatal biomarkers of brain injury are lacking. We hypothesized that candidate biomarker levels determined from DBS can serve as a reliable surrogate for plasma levels. In the context of a phase II multi-center trial evaluating erythropoietin for neuroprotection in neonatal encephalopathy (NE), DBS were collected at enrollment (
- Subjects :
- Male
medicine.medical_specialty
Context (language use)
Neuroprotection
Gastroenterology
Infant, Newborn, Diseases
Internal medicine
medicine
Humans
Prospective Studies
Erythropoietin
Dried Blood Spot Testing
business.industry
Neonatal encephalopathy
Infant, Newborn
Brain
Infant
Interleukin
medicine.disease
Magnetic Resonance Imaging
nervous system diseases
Dried blood spot
Treatment Outcome
surgical procedures, operative
Brain Injuries
Pediatrics, Perinatology and Child Health
Biomarker (medicine)
Female
business
Biomarkers
Follow-Up Studies
medicine.drug
Subjects
Details
- ISSN :
- 15300447 and 00313998
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- Pediatric Research
- Accession number :
- edsair.doi.dedup.....fc5ec43b2c6ef9a3797dbcb38b9cc19b