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The impact of near infrared fluorescence imaging on parathyroid function after total thyroidectomy
- Source :
- Journal of Surgical Oncology.
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Background Compared with conventional thyroidectomy, hypocalcemia rate was reported to be lower after total thyroidectomy (TT) utilizing near infrared fluorescence imaging (NIFI). The aim of this study is to evaluate the impact of NIFI on postoperative parathyroid function after TT. Methods This was a retrospective institutional review board-approved study comparing 100 patients who underwent TT with NIFI guidance and 200 patients without, by the same surgeon. Clinical parameters were compared using χ2 and t test. Results Average number of parathyroid glands identified intraoperatively was similar between two groups. However, rate of incidental parathyroidectomy was higher in conventional (14%) versus NIFI group (6%) (P = .039), despite similar (4% vs 6%, respectively) autotransplantation rates (P = .562). Incidences of transient (6.5% vs 5.0%) and permanent (0.5% vs 0%) hypocalcemia were not statistically different between conventional and NIFI groups (P = NS). Conclusion The use of NIFI during thyroidectomy may decrease the rate of incidental parathyroidectomy by increasing the ability of the surgeon to recognize parathyroid glands with fluorescent contrast distinction. Nevertheless, in contrary to recent reports in literature, postoperative hypocalcemia rate was not altered compared with conventional technique, suggesting that preservation of parathyroid vasculature, rather than an augmented ability to detect the glands, may dominantly affect postoperative function.
- Subjects :
- Male
Parathyroidectomy
medicine.medical_specialty
medicine.medical_treatment
Urology
030230 surgery
Parathyroid Glands
03 medical and health sciences
0302 clinical medicine
Humans
Medicine
Thyroid Neoplasms
Retrospective Studies
Conventional technique
Total thyroidectomy
Hypocalcemia
Goiter
business.industry
Optical Imaging
Thyroidectomy
General Medicine
Middle Aged
Graves Disease
Autotransplantation
medicine.anatomical_structure
Oncology
030220 oncology & carcinogenesis
Calcium
Female
Surgery
Parathyroid gland
business
Subjects
Details
- ISSN :
- 10969098 and 00224790
- Database :
- OpenAIRE
- Journal :
- Journal of Surgical Oncology
- Accession number :
- edsair.doi.dedup.....fbf59f56250636dae813da99ec59af91