Back to Search
Start Over
Serotonergic, Dopaminergic, and Noradrenergic Modulation of Erotic Stimulus Processing in the Male Human Brain
- Source :
- Journal of Clinical Medicine 8(3), 363 (2019). doi:10.3390/jcm8030363, Journal of Clinical Medicine, Vol 8, Iss 3, p 363 (2019), Journal of Clinical Medicine, 8(3):363, Journal of Clinical Medicine
- Publication Year :
- 2019
- Publisher :
- MDPI, 2019.
-
Abstract
- Human sexual behavior is mediated by a complex interplay of cerebral and spinal centers, as well as hormonal, peripheral, and autonomic functions. Neuroimaging studies identified central neural signatures of human sexual responses comprising neural emotional, motivational, autonomic, and cognitive components. However, empirical evidence regarding the neuromodulation of these neural signatures of human sexual responses was scarce for decades. Pharmacological functional magnetic resonance imaging (fMRI) provides a valuable tool to examine the interaction between neuromodulator systems and functional network anatomy relevant for human sexual behavior. In addition, this approach enables the examination of potential neural mechanisms regarding treatment-related sexual dysfunction under psychopharmacological agents. In this article, we introduce common neurobiological concepts regarding cerebral sexual responses based on neuroimaging findings and we discuss challenges and findings regarding investigating the neuromodulation of neural sexual stimulus processing. In particular, we summarize findings from our research program investigating how neural correlates of sexual stimulus processing are modulated by serotonergic, dopaminergic, and noradrenergic antidepressant medication in healthy males.
- Subjects :
- lcsh:Medicine
healthy
Review
Stimulus (physiology)
Serotonergic
03 medical and health sciences
0302 clinical medicine
Neuroimaging
erotic stimulus processing
medicine
human
ddc:610
noradrenaline
serotonin
fMRI
processing
dopamine
erotic stimulus
Neural correlates of consciousness
medicine.diagnostic_test
business.industry
lcsh:R
Cognition
General Medicine
Human brain
030227 psychiatry
medicine.anatomical_structure
Sexual dysfunction
medicine.symptom
Functional magnetic resonance imaging
business
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine 8(3), 363 (2019). doi:10.3390/jcm8030363, Journal of Clinical Medicine, Vol 8, Iss 3, p 363 (2019), Journal of Clinical Medicine, 8(3):363, Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....fb7f3c7cbd6fff665c8b7a31c9e88dc7