Back to Search
Start Over
Cellular therapies in organ transplantation
- Source :
- Transplant International
- Publication Year :
- 2021
- Publisher :
- Frontiers Media SA, 2021.
-
Abstract
- Summary Cellular therapy is a promising tool for improving the outcome of organ transplantation. Various cell types with different immunoregulatory and regenerative properties may find application for specific transplant rejection or injury‐related indications. The current era is crucial for the development of cellular therapies. Preclinical models have demonstrated the feasibility of efficacious cell therapy in transplantation, early clinical trials have shown safety of several of these therapies, and the first steps towards efficacy studies in humans have been made. In this review, we address the current state of the art of cellular therapies in clinical transplantation and discuss monitoring tools and endpoints for these studies.
- Subjects :
- Graft Rejection
medicine.medical_specialty
Cell- and Tissue-Based Therapy
Reviews
Review
030230 surgery
Mesenchymal Stem Cell Transplantation
immunomodulation
Bioinformatics
Organ transplantation
Cell therapy
03 medical and health sciences
0302 clinical medicine
regulatory macrophages
Humans
regulatory T‐cells
Medicine
Transplantation
business.industry
Regeneration (biology)
Mesenchymal Stem Cells
Organ Transplantation
medicine.disease
Transplant rejection
Clinical trial
regeneration
030211 gastroenterology & hepatology
cell therapy
mesenchymal stromal cells
business
Subjects
Details
- ISSN :
- 14322277 and 09340874
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Transplant International
- Accession number :
- edsair.doi.dedup.....fb0416700f51351b107be4cd08d6f118
- Full Text :
- https://doi.org/10.1111/tri.13789